Menopause Studies

What is FRAN?

The FRAN Study (Flushing Reduction Associated with Nitrates) is a 12-week randomized, controlled, clinical trial of a transdermal nitrate patch compared to placebo women with menopausal hot flash symptoms. You may be eligible for the study if you are:

  • Are between the ages 40 and 62
  • Have multiple hot flashes per day
  • Do not have diabetes or cardiovascular disease
  • Are willing to wear a nitrate patch or a placebo patch in a randomized trial

Participation in this study includes 6 clinic visits over 16 weeks at the UCSF Mount Zion campus or at a satellite office in Oakland, CA. 

Why is this study being done?

The purpose of the FRAN study is to see if nitrate patches can be used to reduce menopausal hot flash symptoms.

How do I participate?

To get more information and find out if you are eligible, please call (415) 885-7547 or email hotflash@ucsfmedctr.org.