Alison Huang, MD, MPhil, MAS

Professor in Residence

Dr. Alison Huang is Professor of Medicine, Urology, and Epidemiology & Biostatistics; Director of Research for General Internal Medicine at UCSF Health; Director of the UCSF Women's Health Clinical Research Center; and a clinical scientist dedicated to advancing scientific understanding and improving management of the impact of aging on women’s health and genitourinary health. She leads a multidisciplinary team of clinical and translational scientists in investigating shared factors underlying relationships between common genitourinary health conditions and overlapping aging syndromes such as cognitive and physical function decline, sleep disruption, and depression. She has designed and led multiple NIH-funded randomized trials of pharmacologic, behavioral, and integrative health interventions in midlife and older women that leverage findings from her epidemiological research on urinary incontinence, overactive bladder, urogenital atrophy, and menopause symptoms. She has also developed and validated patient-reported outcome measures of genitourinary health and function in older women of diverse backgrounds that have been adopted and translated into multiple languages by investigators in the U.S. and internationally. She directs NIH-funded training programs and teaches clinical research methods courses for early-stage investigators based in the UCSF Department of Epidemiology & Biostatistics and the UCSF Clinical & Translational Science Institute. With the support of an NIH K24 mentoring award, she mentors early-stage investigators in designing clinical research studies and launching research careers focused on aging women's health, genitourinary health, and behavioral, pharmacologic, and integrative health interventions. As a general internal medicine physician, she provides primary care to adults of all ages in UCSF Health's General Medicine Practice.

Publications: 

Prescription of estrogen therapy and sedating medications in older women in a national ambulatory care sample.

Journal of the American Geriatrics Society

Hunter MM, Lisha NE, Huang AJ

Older adults with overlapping caregiving responsibilities and care needs in a U.S. national community-based sample.

Journal of the American Geriatrics Society

Semere W, Yank V, Lisha NE, Lindquist LA, Huang AJ

Military Sexual Trauma and Menopause Symptoms Among Midlife Women Veterans.

Journal of general internal medicine

Travis KJ, Huang AJ, Maguen S, Inslicht S, Byers AL, Seal KH, Gibson CJ

Total and Free 25-hydroxyvitamin D Concentrations and Risk of Urinary Incontinence in Women Participating in Nurses Health Studies I & II.

The American journal of the medical sciences

Tangpricha V, Markland AD, Vaughan CP, Huang AJ, Grodstein F

Social strain and conflict among older community-dwelling adults serving as caregivers: Findings from a national sample.

Journal of the American Geriatrics Society

Nyarko-Odoom A, Kotwal A, Lisha NE, Yank V, Huang AJ

Lifetime history of interpersonal partner violence is associated with insomnia among midlife women veterans.

Menopause (New York, N.Y.)

Goldstein LA, Jakubowski KP, Huang AJ, Seal KH, Maguen S, Inslicht SS, Byers AL, Gibson CJ

Elder Mistreatment Experienced by Older Caregiving Adults: Results from a National Community-Based Sample.

Journal of general internal medicine

Nyarko-Odoom A, Lisha NE, Yank V, Kotwal A, Balogun S, Huang AJ

Vitamin D supplements and prevalent overactive bladder in women from midlife through older ages.

Menopause (New York, N.Y.)

Vaughan CP, Markland AD, Huang AJ, Tangpricha V, Grodstein F

Effect of Vitamin D Supplementation on Overactive Bladder and Urinary Incontinence Symptoms in Older Men: Ancillary Findings from a Randomized Trial.

The Journal of urology

Markland AD, Vaughan C, Huang AJ, Kim E, Bubes VY, Tangpricha V, Buring J, Lee IM, Cook N, Manson JE, Grodstein F

Veterans Health Administration Screening for Military Sexual Trauma May Miss Over Half of Cases Among Midlife Women Veterans.

Women's health issues : official publication of the Jacobs Institute of Women's Health

Hargrave AS, Maguen S, Inslicht SS, Byers AL, Seal KH, Huang AJ, Gibson CJ

Racial/ethnic disparities in the diagnosis and management of menopause symptoms among midlife women veterans.

Menopause (New York, N.Y.)

Blanken A, Gibson CJ, Li Y, Huang AJ, Byers AL, Maguen S, Inslicht S, Seal K

Considerations for integrated cognitive behavioural treatment for older adults with coexisting nocturia and insomnia.

Age and ageing

Vaughan CP, Markland AD, Huang AJ, Alessi CA, Guzman A, Martin JL, Bliwise DL, Johnson Ii TM, Burgio KL, Fung CH

Rapid Conversion of a Group-Based Yoga Trial for Diverse Older Women to Home-Based Telehealth: Lessons Learned Using Zoom to Deliver Movement-Based Interventions.

Journal of integrative and complementary medicine

Huang AJ, Chesney MA, Schembri M, Pawlowsky S, Nicosia F, Subak LL

Effect of Vitamin D Supplementation on Urinary Incontinence in Older Women: Ancillary Findings from a Randomized Trial.

American journal of obstetrics and gynecology

Markland AD, Vaughan C, Huang A, Kim E, Bubes VY, Tangpricha V, Buring J, Lee IM, Cook N, Manson JE, Grodstein F

Interpersonal violence and painful bladder symptoms in community-dwelling midlife to older women.

American journal of obstetrics and gynecology

Raphael E, Van Den Eeden SK, Gibson CJ, Tonner C, Thom DH, Subak L, Huang AJ

Formal and informal social participation and elder mistreatment in a national sample of older adults.

Journal of the American Geriatrics Society

Yang EZ, Kotwal AA, Lisha NE, Wong JS, Huang AJ

Editorial Comment.

The Journal of urology

Workplace Sexual Harassment: Potential Long-term Associations with Psychological Function in Older Adults.

Journal of general internal medicine

Gibson CJ, Lisha N, Lalchandani P, Huang AJ

Early Life Sexual Trauma and Later Life Genitourinary Dysfunction and Functional Disability in Women.

Journal of general internal medicine

Lalchandani P, Lisha N, Gibson C, Huang AJ

Vitamin D Intake and Progression of Urinary Incontinence in Women.

Urology

Vaughan CP, Markland AD, Huang AJ, Tangpricha V, Grodstein F

Vitamin D intake and the 10-year risk of urgency urinary incontinence in women.

The Journal of steroid biochemistry and molecular biology

Markland AD, Vaughan C, Huang A, Tangpricha V, Grodstein F

Patient-Centered Change in the Day-to-Day Impact of Postmenopausal Vaginal Symptoms: Results from a Multicenter Randomized Trial.

American journal of obstetrics and gynecology

Gibson CJ, Huang AJ, Larson JC, Mitchell C, Diem S, Lacroix A, Newton KM, Reed SD, Guthrie KA

Interpersonal Trauma as a Marker of Risk for Urinary Tract Dysfunction in Midlife and Older Women.

Obstetrics and gynecology

Boyd BAJ, Gibson CJ, Van Den Eeden SK, McCaw B, Subak LL, Thom D, Huang AJ

Beyond the bladder: poor sleep in women with overactive bladder syndrome.

American journal of obstetrics and gynecology

Savoie MB, Lee KA, Subak LL, Hernandez C, Schembri M, Fung CH, Grady D, Huang AJ

Convergent-Divergent Validity and Correlates of the Day-to-Day Impact of Vaginal Aging Domain Scales in the MsFLASH Vaginal Health Trial.

The journal of sexual medicine

Hunter MM, Guthrie KA, Larson JC, Reed SD, Mitchell CM, Diem SJ, LaCroix AZ, Huang AJ

A Randomized Controlled Trial of Device-Guided Slow-Paced Respiration In Women with Overactive Bladder Syndrome.

The Journal of urology

Huang AJ, Grady D, Mendes WB, Hernandez C, Schembri M, Subak LL

Menopausal Symptoms and Higher Risk Opioid Prescribing in a National Sample of Women Veterans with Chronic Pain.

Journal of general internal medicine

Gibson CJ, Li Y, Huang AJ, Rife T, Seal KH

Menopause symptoms and chronic pain in a national sample of midlife women veterans.

Menopause (New York, N.Y.)

Gibson CJ, Li Y, Bertenthal D, Huang AJ, Seal KH

Changes in Sexual Functioning in Women and Men in the 5 Years After Bariatric Surgery.

JAMA surgery

Steffen KJ, King WC, White GE, Subak LL, Mitchell JE, Courcoulas AP, Flum DR, Strain G, Sarwer DB, Kolotkin RL, Pories W, Huang AJ

Hot flushes, coronary heart disease, and hormone therapy in postmenopausal women.

Menopause (New York, N.Y.)

Huang AJ, Sawaya GF, Vittinghoff E, Lin F, Grady D

A group-based yoga program for urinary incontinence in ambulatory women: feasibility, tolerability, and change in incontinence frequency over 3 months in a single-center randomized trial.

American journal of obstetrics and gynecology

Huang AJ, Chesney M, Lisha N, Vittinghoff E, Schembri M, Pawlowsky S, Hsu A, Subak L

Interpersonal trauma and aging-related genitourinary dysfunction in a national sample of older women.

American journal of obstetrics and gynecology

Gibson CJ, Lisha NE, Walter LC, Huang AJ

Urinary Incontinence in a National Cohort of Older Women: Implications for Caregiving and Care Dependence.

Journal of women's health (2002)

Yang E, Lisha NE, Walter L, Obedin-Maliver J, Huang AJ

Sleep Quality and Daytime Sleepiness Among Women With Urgency Predominant Urinary Incontinence.

Female pelvic medicine & reconstructive surgery

Winkelman WD, Warsi A, Huang AJ, Schembri M, Rogers RG, Richter HE, Myers DL, Kraus SR, Johnson KC, Hess R, Gregory T, Bradley CS, Arya LA, Brown JS, Stone KL, Subak LL

Association of Pharmacologic Treatment of Urgency Urinary Incontinence With Sleep Quality and Daytime Sleepiness.

Obstetrics and gynecology

Warsi QA, Huang AJ, Hess R, Arya LA, Richter HE, Bradley CS, Rogers RG, Myers DL, Johnson KC, Winkelman WD, Gregory WT, Kraus SR, Schembri M, Brown JS, Stone KL, Subak LL

Development and Feasibility of a Group-Based Therapeutic Yoga Program for Women with Chronic Pelvic Pain.

Pain medicine (Malden, Mass.)

Huang AJ, Rowen TS, Abercrombie P, Subak LL, Schembri M, Plaut T, Chao MT

Nocturia is Associated with Poor Sleep Quality Among Older Women in the Study of Osteoporotic Fractures.

Journal of the American Geriatrics Society

Fung CH, Vaughan CP, Markland AD, Huang AJ, Mitchell MN, Bliwise DL, Ancoli-Israel S, Redline S, Alessi CA, Stone K

Cardiac autonomic function and hot flashes among perimenopausal and postmenopausal women.

Menopause (New York, N.Y.)

Gibson CJ, Mendes WB, Schembri M, Grady D, Huang AJ

Urine leakage during sexual activity among ethnically diverse, community-dwelling middle-aged and older women.

American journal of obstetrics and gynecology

Munaganuru N, Van Den Eeden SK, Creasman J, Subak LL, Strano-Paul L, Huang AJ

Modifiers of Response to Treatment With Fesoterodine for Urgency-Predominant Urinary Incontinence in a Randomized Controlled Trial.

Female pelvic medicine & reconstructive surgery

Winkelman WD, Huang AJ, Schembri M, Rogers RG, Richter H, Myers DL, Kraus SR, Johnson KC, Hess R, Gregory T, Bradley CS, Arya L, Brown JS, Subak LL

Urinary Incontinence in Older Women: The Role of Body Composition and Muscle Strength: From the Health, Aging, and Body Composition Study.

Journal of the American Geriatrics Society

Suskind AM, Cawthon PM, Nakagawa S, Subak LL, Reinders I, Satterfield S, Cummings S, Cauley JA, Harris T, Huang AJ

Sexual functioning of men and women with severe obesity before bariatric surgery.

Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery

Steffen KJ, King WC, White GE, Subak LL, Mitchell JE, Courcoulas AP, Flum DR, Strain G, Sarwer DB, Kolotkin RL, Pories W, Huang AJ

Continuous transdermal nitroglycerin therapy for menopausal hot flashes: a single-arm, dose-escalation trial.

Menopause (New York, N.Y.)

Huang AJ, Cummings SR, Schembri M, Vittinghoff E, Ganz P, Grady D

Bladder Symptoms in the Early Menopausal Transition.

Journal of women's health (2002)

Jones HJ, Huang AJ, Subak LL, Brown JS, Lee KA

Predictors of impact of vaginal symptoms in postmenopausal women.

Menopause (New York, N.Y.)

Hunter MM, Nakagawa S, Van Den Eeden SK, Kuppermann M, Huang AJ

Bridging the gap: determinants of undiagnosed or untreated urinary incontinence in women.

American journal of obstetrics and gynecology

Duralde ER, Walter LC, Van Den Eeden SK, Nakagawa S, Subak LL, Brown JS, Thom DH, Huang AJ

Urinary Incontinence Before and After Bariatric Surgery.

JAMA internal medicine

Subak LL, King WC, Belle SH, Chen JY, Courcoulas AP, Ebel FE, Flum DR, Khandelwal S, Pender JR, Pierson SK, Pories WJ, Steffen KJ, Strain GW, Wolfe BM, Huang AJ

Device-guided slow-paced respiration for menopausal hot flushes: a randomized controlled trial.

Obstetrics and gynecology

Huang AJ, Phillips S, Schembri M, Vittinghoff E, Grady D

Day-to-Day Impact of Vaginal Aging questionnaire: a multidimensional measure of the impact of vaginal symptoms on functioning and well-being in postmenopausal women.

Menopause (New York, N.Y.)

Huang AJ, Gregorich SE, Kuppermann M, Nakagawa S, Van Den Eeden SK, Brown JS, Richter HE, Walter LC, Thom D, Stewart AL

The burden of nocturia among middle-aged and older women.

Obstetrics and gynecology

Hsu A, Nakagawa S, Walter LC, Van Den Eeden SK, Brown JS, Thom DH, Lee SJ, Huang AJ

Predictors of urinary incontinence in community-dwelling frail older adults with diabetes mellitus in a cross-sectional study.

BMC geriatrics

Hsu A, Conell-Price J, Stijacic Cenzer I, Eng C, Huang AJ, Rice-Trumble K, Lee SJ

The impact of multimorbidity on sexual function in middle-aged and older women: beyond the single disease perspective.

The journal of sexual medicine

Appa AA, Creasman J, Brown JS, Van Den Eeden SK, Thom DH, Subak LL, Huang AJ

A group-based yoga therapy intervention for urinary incontinence in women: a pilot randomized trial.

Female pelvic medicine & reconstructive surgery

Huang AJ, Jenny HE, Chesney MA, Schembri M, Subak LL

Childbirth and female sexual function later in life.

Obstetrics and gynecology

Fehniger JE, Brown JS, Creasman JM, Van Den Eeden SK, Thom DH, Subak LL, Huang AJ

Sex hormone levels and risk of breast cancer with estrogen plus progestin.

Journal of the National Cancer Institute

Farhat GN, Parimi N, Chlebowski RT, Manson JE, Anderson G, Huang AJ, Vittinghoff E, Lee JS, Lacroix AZ, Cauley JA, Jackson R, Grady D, Lane DS, Phillips L, Simon MS, Cummings SR

Clinical predictors and significance of postvoid residual volume in women with diabetes.

Diabetes research and clinical practice

Appa AA, Brown JS, Creasman J, Van Den Eeden SK, Subak LL, Thom DH, Ferrara A, Huang AJ

Long-term efficacy and safety of questionnaire-based initiation of urgency urinary incontinence treatment.

American journal of obstetrics and gynecology

Hess R, Huang AJ, Richter HE, Ghetti CC, Sung VW, Barrett-Connor E, Gregory WT, Pinkerton JV, Bradley CS, Kraus SR, Rogers RG, Subak LL, Johnson KC, Arya LA, Schembri M, Brown JS

Fecal incontinence decreases sexual quality of life, but does not prevent sexual activity in women.

Diseases of the colon and rectum

Imhoff LR, Brown JS, Creasman JM, Subak LL, Van den Eeden SK, Thom DH, Varma MG, Huang AJ

Diabetes mellitus and sexual function in middle-aged and older women.

Obstetrics and gynecology

Copeland KL, Brown JS, Creasman JM, Van Den Eeden SK, Subak LL, Thom DH, Ferrara A, Huang AJ

Pharmacologic treatment for urgency-predominant urinary incontinence in women diagnosed using a simplified algorithm: a randomized trial.

American journal of obstetrics and gynecology

Huang AJ, Hess R, Arya LA, Richter HE, Subak LL, Bradley CS, Rogers RG, Myers DL, Johnson KC, Gregory WT, Kraus SR, Schembri M, Brown JS

Clinical significance of postvoid residual volume in older ambulatory women.

Journal of the American Geriatrics Society

Huang AJ, Brown JS, Boyko EJ, Moore EE, Scholes D, Walter LC, Lin F, Vittinghoff E, Fihn SD

Sex hormone levels and risks of estrogen receptor-negative and estrogen receptor-positive breast cancers.

Journal of the National Cancer Institute

Farhat GN, Cummings SR, Chlebowski RT, Parimi N, Cauley JA, Rohan TE, Huang AJ, Vitolins M, Hubbell FA, Manson JE, Cochrane BB, Lane DS, Lee JS

An intensive behavioral weight loss intervention and hot flushes in women.

Archives of internal medicine

Huang AJ, Subak LL, Wing R, West DS, Hernandez AL, Macer J, Grady D

Vaginal symptoms in postmenopausal women: self-reported severity, natural history, and risk factors.

Menopause (New York, N.Y.)

Huang AJ, Moore EE, Boyko EJ, Scholes D, Lin F, Vittinghoff E, Fihn SD

The day-to-day impact of urogenital aging: perspectives from racially/ethnically diverse women.

Journal of general internal medicine

Huang AJ, Luft J, Grady D, Kuppermann M

Hot flushes, coronary heart disease, and hormone therapy in postmenopausal women.

Menopause (New York, N.Y.)

Huang AJ, Sawaya GF, Vittinghoff E, Lin F, Grady D

Sexual function and aging in racially and ethnically diverse women.

Journal of the American Geriatrics Society

Huang AJ, Subak LL, Thom DH, Van Den Eeden SK, Ragins AI, Kuppermann M, Shen H, Brown JS

Mixed urinary incontinence: greater impact on quality of life.

The Journal of urology

Frick AC, Huang AJ, Van den Eeden SK, Knight SK, Creasman JM, Yang J, Ragins AI, Thom DH, Brown JS

Ending cervical cancer screening: attitudes and beliefs from ethnically diverse older women.

American journal of obstetrics and gynecology

Sawaya GF, Iwaoka-Scott AY, Kim S, Wong ST, Huang AJ, Washington AE, Pérez-Stable EJ

Development and validation of a sexual functioning measure for use in diverse women's health outcome studies.

American journal of obstetrics and gynecology

Learman LA, Huang AJ, Nakagawa S, Gregorich SE, Kuppermann M

Preferences for human papillomavirus testing with routine cervical cancer screening in diverse older women.

Journal of general internal medicine

Huang AJ, Pérez-Stable EJ, Kim SE, Wong ST, Kaplan CP, Walsh JM, Iwaoka-Scott AY, Sawaya GF

Persistent hot flushes in older postmenopausal women.

Archives of internal medicine

Huang AJ, Grady D, Jacoby VL, Blackwell TL, Bauer DC, Sawaya GF

The effect of ultralow-dose transdermal estradiol on sexual function in postmenopausal women.

American journal of obstetrics and gynecology

Huang A, Yaffe K, Vittinghoff E, Kuppermann M, Addis I, Hanes V, Quan J, Grady D

Endogenous estrogen levels and the effects of ultra-low-dose transdermal estradiol therapy on bone turnover and BMD in postmenopausal women.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Huang AJ, Ettinger B, Vittinghoff E, Ensrud KE, Johnson KC, Cummings SR

Hot flushes, bone mineral density, and fractures in older postmenopausal women.

Obstetrics and gynecology

Huang A, Grady D, Blackwell T, Bauer D

Urinary incontinence in older community-dwelling women: the role of cognitive and physical function decline.

Obstetrics and gynecology

Huang AJ, Brown JS, Thom DH, Fink HA, Yaffe K

Quality-of-life impact and treatment of urinary incontinence in ethnically diverse older women.

Archives of internal medicine

Huang AJ, Brown JS, Kanaya AM, Creasman JM, Ragins AI, Van Den Eeden SK, Thom DH

Urinary incontinence and pelvic floor dysfunction in Asian-American women.

American journal of obstetrics and gynecology

Huang AJ, Thom DH, Kanaya AM, Wassel-Fyr CL, Van den Eeden SK, Ragins AI, Subak LL, Brown JS

Health plans' coverage determinations for technology-based interventions: the case of electrical bone growth stimulation.

The American journal of managed care

Huang AJ, Gemperli MP, Bergthold L, Singer SS, Garber A

Characterization of mutated transforming growth factor-beta s which possess unique biological properties.

Biochemistry

Qian SW, Burmester JK, Sun PD, Huang A, Ohlsen DJ, Suardet L, Flanders KC, Davies D, Roberts AB, Sporn MB

Characterization of distinct functional domains of transforming growth factor beta.

Proceedings of the National Academy of Sciences of the United States of America

Burmester JK, Qian SW, Roberts AB, Huang A, Amatayakul-Chantler S, Suardet L, Odartchenko N, Madri JA, Sporn MB