Bladder Studies

The UCSF Women's Health Clinical Research Center conducts a variety of research studies designed to further understand the causes, diagnosis, and treatments of urinary incontinence, overactive bladder, and urinary symptoms in women. Our goal is to investigate novel treatments to improve urinary symptoms. Please read more about current research studies below. Or click on the "Prescreen" button to answer a few questions to see if you may qualify for one of our studies.

TRIUMPH Study

What is TRIuMPh?

The TRIuMPh Study (Treatment of Incontinence without Memory Problems) is an 8-week randomized, controlled, pilot clinical trial of mirabegron compared to a standard anticholinergic therapy in elderly women with urgency urinary incontinence.   You may be eligible for the study if you are:

  • Are a woman, at least 65 years old
  • Frequently experience strong sudden urges to urinate
  • Frequently experience unwanted urine leakages
  • Are willing to answer questionnaires
  • Are willing to take study medication daily for 8 weeks

Participation in this study includes 4 clinic visits over 8 weeks at our UCSF Mount Zion campus.  Those who qualify will receive study medication, free of charge, for 8 weeks.

Why is this study being done?

The purpose of this study is to gather information about the feasibility of recruiting and randomizing women with urgency urinary incontinence to tolterodine tartrate or mirabegron.

While tolterodine tartrate and mirabegron are FDA-approved for treatment of urgency urinary incontinence, we do not know whether it is feasible to recruit women aged 65 years of age or older. This study will also allow us to collect preliminary data to see if there is a difference in the effects of mirabegron and tolterodine tartrate on cognitive function in women with urgency incontinence.

How do I participate?

To get more information and find out if you are eligible, please call (415) 885-7547 or email takecontrol@ucsf.edu.

Or CLICK HERE to answer a few questions to see if you qualify.

CURE Study

What is CURE?

The CURE Study (Controlling Urgency by Relaxation Exercises) is a randomized controlled trial comparing two kinds of relaxation exercises to treat urinary urgency (a.k.a. overactive bladder) in women. You may be eligible for the study if you are:

  • Are a woman, at least 21 years old
  • Can’t seem to get to the bathroom fast enough
  • Are willing to use a small portable device to practice daily relaxation exercises involving slow breathing or music listening

Participation in this study includes 5 visits over 14 weeks at our UCSF Mount Zion campus or in our Oakland office.  Those who qualify may be compensated up to $120 in gift cards for their participation.

Why is this study being done?

The purpose of this study is to compare the effects of two types of relaxation therapy – paced respiration or music therapy -- to treat urinary urgency (overactive bladder), in women. In this study, a small device will be used either to guide your breathing rate or play specially-designed relaxing music.

How do I participate?

To get more information and find out if you are eligible, please call (415) 885-7547 or email takecontrol@ucsf.edu. 

Or CLICK HERE to answer a few questions to see if you qualify.

LILA Study

What is LILA?

The LILA Study (Lessening Incontinence through Low-impact Activity) is a pilot, randomized, parallel-group trial of a group-based yoga therapy program versus physical conditioning therapy program for treatment of urinary incontinence in women. You may be eligible for the study if you are:

  • Are a woman, at least 50 years old
  • Frequently experience unwanted urine leakages
  • Are willing to answer questionnaires
  • Are willing to attend a yoga or physical conditioning program 2 times a week, for 12 weeks

Participation in this study includes 4 clinic visits over 12 weeks at our UCSF Mount Zion campus.  Those who qualify may be compensated for their time.

Why is this study being done?

The purpose of this study is to gather information about the effects of a group-based yoga or physical conditioning program on urinary incontinence in women.

How do I participate?

To get more information and find out if you are eligible, please call (415) 885-7547 or email takecontrol@ucsf.edu. 

Or CLICK HERE to answer a few questions to see if you qualify.