Sabra Inslicht, PhD

Adjunct Professor

My research goals include: 1) identifying psychobiological causes and consequences of traumatic stress symptoms; 2) utilizing fear conditioning and extinction models to better understand PTSD; 3) characterizing sex differences in the biology of PTSD; 4) improving measurement techniques in the laboratory and the field such as with mobile health devices; and 5) conducting research that will inform novel interventions for ameliorating prolonged PTSD responses.

Publications: 

An exploratory study on lipidomic profiles in a cohort of individuals with posttraumatic stress disorder.

Scientific reports

Bhargava A, Knapp JD, Fiehn O, Neylan TC, Inslicht SS

Tumor Suppressor MicroRNAs in Clinical and Preclinical Trials for Neurological Disorders.

Pharmaceuticals (Basel, Switzerland)

Lui A, Do T, Alzayat O, Yu N, Phyu S, Santuya HJ, Liang B, Kailash V, Liu D, Inslicht SS, Shahlaie K, Liu D

The lipidome of posttraumatic stress disorder.

bioRxiv : the preprint server for biology

Bhargava A, Knapp JD, Fiehn O, Neylan TC, Inslicht SS

The Middle-Out Approach to reconceptualizing, assessing, and analyzing traumatic stress reactions.

Journal of traumatic stress

Adams SW, Layne CM, Contractor AA, Allwood MA, Armour C, Inslicht SS, Maguen S

Military Sexual Trauma and Menopause Symptoms Among Midlife Women Veterans.

Journal of general internal medicine

Travis KJ, Huang AJ, Maguen S, Inslicht S, Byers AL, Seal KH, Gibson CJ

Lifetime history of interpersonal partner violence is associated with insomnia among midlife women veterans.

Menopause (New York, N.Y.)

Goldstein LA, Jakubowski KP, Huang AJ, Seal KH, Maguen S, Inslicht SS, Byers AL, Gibson CJ

Impact of hormonal contraceptives on sex differences in fear conditioning and fear extinction in PTSD.

Learning & memory (Cold Spring Harbor, N.Y.)

Bartholomew ME, Rozalski V, Richards A, Gurdock J, Thornton M, Fee C, Lipshitz SL, Metzler TJ, Neylan TC, Inslicht SS

Comparing Heart Rate Analytical Methods to Examine Engagement During Imaginal Prolonged Exposure Therapy: Multicase Study.

American journal of psychotherapy

Cowden Hindash AH, Diamond Altman A, Levitan J, Inslicht SS

Veterans Health Administration Screening for Military Sexual Trauma May Miss Over Half of Cases Among Midlife Women Veterans.

Women's health issues : official publication of the Jacobs Institute of Women's Health

Hargrave AS, Maguen S, Inslicht SS, Byers AL, Seal KH, Huang AJ, Gibson CJ

Racial/ethnic disparities in the diagnosis and management of menopause symptoms among midlife women veterans.

Menopause (New York, N.Y.)

Blanken A, Gibson CJ, Li Y, Huang AJ, Byers AL, Maguen S, Inslicht S, Seal K

Chemical set enrichment analysis: Novel insights into sex-specific alterations in primary metabolites in posttraumatic stress and disturbed sleep.

Clinical and translational medicine

Bhargava A, Fan S, Lujan CR, Fiehn O, Neylan TC, Inslicht SS

Randomized controlled experimental study of hydrocortisone and D-cycloserine effects on fear extinction in PTSD.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

Inslicht SS, Niles AN, Metzler TJ, Lipshitz SL, Otte C, Milad MR, Orr SP, Marmar CR, Neylan TC

Ventromedial and insular cortical volume moderates the relationship between BDNF Val66Met and threat sensitivity.

Journal of psychiatric research

Young DA, Chao LL, Zhang H, Metzler T, Ross J, Richards A, O'Donovan A, Inslicht SS, Neylan TC

COVID-19 related moral injury: Associations with pandemic-related perceived threat and risky and protective behaviors.

Journal of psychiatric research

Khan AJ, Nishimi K, Tripp P, Maven D, Jiha A, Woodward E, Inslicht S, Richards A, Neylan TC, Maguen S, O'Donovan A

Examining the Effect of Sleep Disruption on the Neural Correlates of Fear Extinction.

Biological psychiatry. Cognitive neuroscience and neuroimaging

Straus LD, Richards A, Inslicht SS, Dolsen EA, Neylan TC

Acute cognitive effects of the hypocretin receptor antagonist almorexant relative to zolpidem and placebo: a randomized clinical trial.

Sleep

Neylan TC, Richards A, Metzler TJ, Ruoff LM, Varbel J, O'Donovan A, Sivasubramanian M, Motraghi T, Hlavin J, Batki SL, Inslicht SS, Samuelson K, Morairty SR, Kilduff TS

Impulsivity as a multifactorial construct and its relationship to PTSD severity and threat sensitivity.

Psychiatry research

Young DA, Neylan TC, Zhang H, O'Donovan A, Inslicht SS

Validation of sleep measurement in a multisensor consumer grade wearable device in healthy young adults.

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine

Kanady JC, Ruoff L, Straus LD, Varbel J, Metzler T, Richards A, Inslicht SS, O'Donovan A, Hlavin J, Neylan TC

Gender Differences in Threat Biases: Trauma Type Matters in Posttraumatic Stress Disorder.

Journal of traumatic stress

Cowden Hindash AH, Lujan C, Howard M, O'Donovan A, Richards A, Neylan TC, Inslicht SS

Psychophysiological treatment outcomes: Corticotropin-releasing factor type 1 receptor antagonist increases inhibition of fear-potentiated startle in PTSD patients.

Psychophysiology

Jovanovic T, Duncan EJ, Kaye J, Garza K, Norrholm SD, Inslicht SS, Neylan TC, Mathew SJ, Iosifescu D, Rothbaum BO, Mayberg HS, Dunlop BW

Altered overnight levels of pro-inflammatory cytokines in men and women with posttraumatic stress disorder.

Psychoneuroendocrinology

Küffer A, Straus LD, Prather AA, Inslicht SS, Richards A, Shigenaga JK, Madden E, Metzler TJ, Neylan TC, O'Donovan A

Gender Differences in Cardiovascular Risk Related to Diabetes and Posttraumatic Stress Disorder.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

Gibson CJ, Li Y, Inslicht SS, Seal KH, Byers AL

Association among anterior cingulate cortex volume, psychophysiological response, and PTSD diagnosis in a Veteran sample.

Neurobiology of learning and memory

Young DA, Chao L, Neylan TC, O'Donovan A, Metzler TJ, Inslicht SS

Effects of Threat Context, Trauma History, and Posttraumatic Stress Disorder Status on Physiological Startle Reactivity in Gulf War Veterans.

Journal of traumatic stress

Niles AN, Luxenberg A, Neylan TC, Inslicht SS, Richards A, Metzler TJ, Hlavin J, Deng J, O'Donovan A

Patterns of Zolpidem Use in Male and Female Veterans Following Revised FDA Dosing Guidelines.

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine

Inslicht SS, Neylan TC

The interaction of BDNF Val66Met, PTSD, and child abuse on psychophysiological reactivity and HPA axis function in a sample of Gulf War Veterans.

Journal of affective disorders

Young DA, Neylan TC, O'Donovan A, Metzler T, Richards A, Ross JA, Inslicht SS

Deployment Anxiety Reduction Training: A Pilot Study of Acceptability and Feasibility in Current or Recent Active Duty Service Members.

Military medicine

McCaslin SE, Herbst ED, Armitage NH, Allen I, Neylan T, Becket-Davenport C, Choucroun G, Best S, Inslicht SS

An Open-Label Study of Doxazosin Extended-Release for PTSD: Findings and Recommendations for Future Research on Doxazosin.

Focus (American Psychiatric Publishing)

Richards A, Inslicht S, Ruoff LM, Metzler TJ, Goldstein LA, Chapman CM, Hubachek SQ, Neylan TC

Subjective Sleep Related to Post Traumatic Stress Disorder Symptoms among Trauma-Exposed Men and Women.

Behavioral sleep medicine

Gibson CJ, Richards A, Villanueva C, Barrientos M, Neylan TC, Inslicht SS

Sleep and hypothalamic pituitary adrenal axis responses to metyrapone in posttraumatic stress disorder.

Psychoneuroendocrinology

Inslicht SS, Rao MN, Richards A, O'Donovan A, Gibson CJ, Baum T, Metzler TJ, Neylan TC

Assessment of skin conductance in African American and Non-African American participants in studies of conditioned fear.

Psychophysiology

Alexandra Kredlow M, Pineles SL, Inslicht SS, Marin MF, Milad MR, Otto MW, Orr SP

Sleep and Cognitive Performance From Teens To Old Age: More Is Not Better.

Sleep

Richards A, Inslicht SS, Metzler TJ, Mohlenhoff BS, Rao MN, O'Donovan A, Neylan TC

Metabolic risk factors and posttraumatic stress disorder: the role of sleep in young, healthy adults.

Psychosomatic medicine

Talbot LS, Rao MN, Cohen BE, Richards A, Inslicht SS, O'Donovan A, Maguen S, Metzler TJ, Neylan TC

Hyperinsulinemic response to oral glucose challenge in individuals with posttraumatic stress disorder.

Psychoneuroendocrinology

Rao MN, Chau A, Madden E, Inslicht S, Talbot L, Richards A, O'Donovan A, Ruoff L, Grunfeld C, Neylan TC

Prospective study of police officer spouse/partners: a new pathway to secondary trauma and relationship violence?

PloS one

Meffert SM, Henn-Haase C, Metzler TJ, Qian M, Best S, Hirschfeld A, McCaslin S, Inslicht S, Neylan TC, Marmar CR

Sex differences in neurosteroid and hormonal responses to metyrapone in posttraumatic stress disorder.

Psychopharmacology

Inslicht SS, Richards A, Madden E, Rao MN, O'Donovan A, Talbot LS, Rucker E, Metzler TJ, Hauger RL, Neylan TC

Cortisol response to an experimental stress paradigm prospectively predicts long-term distress and resilience trajectories in response to active police service.

Journal of psychiatric research

Galatzer-Levy IR, Steenkamp MM, Brown AD, Qian M, Inslicht S, Henn-Haase C, Otte C, Yehuda R, Neylan TC, Marmar CR

Sex differences in objective measures of sleep in post-traumatic stress disorder and healthy control subjects.

Journal of sleep research

Richards A, Metzler TJ, Ruoff LM, Inslicht SS, Rao M, Talbot LS, Neylan TC

Sex differences in fear conditioning in posttraumatic stress disorder.

Journal of psychiatric research

Inslicht SS, Metzler TJ, Garcia NM, Pineles SL, Milad MR, Orr SP, Marmar CR, Neylan TC

Cortisol awakening response prospectively predicts peritraumatic and acute stress reactions in police officers.

Biological psychiatry

Inslicht SS, Otte C, McCaslin SE, Apfel BA, Henn-Haase C, Metzler T, Yehuda R, Neylan TC, Marmar CR

Pretraumatic prolonged elevation of salivary MHPG predicts peritraumatic distress and symptoms of post-traumatic stress disorder.

Journal of psychiatric research

Apfel BA, Otte C, Inslicht SS, McCaslin SE, Henn-Haase C, Metzler TJ, Makotkine I, Yehuda R, Neylan TC, Marmar CR

Protective factors for posttraumatic stress disorder symptoms in a prospective study of police officers.

Psychiatry research

Yuan C, Wang Z, Inslicht SS, McCaslin SE, Metzler TJ, Henn-Haase C, Apfel BA, Tong H, Neylan TC, Fang Y, Marmar CR

Adaptation effects to sleep studies in participants with and without chronic posttraumatic stress disorder.

Psychophysiology

Herbst E, Metzler TJ, Lenoci M, McCaslin SE, Inslicht S, Marmar CR, Neylan TC

A prospective study of predictors of depression symptoms in police.

Psychiatry research

Wang Z, Inslicht SS, Metzler TJ, Henn-Haase C, McCaslin SE, Tong H, Neylan TC, Marmar CR

Routine work environment stress and PTSD symptoms in police officers.

The Journal of nervous and mental disease

Maguen S, Metzler TJ, McCaslin SE, Inslicht SS, Henn-Haase C, Neylan TC, Marmar CR

Family psychiatric history, peritraumatic reactivity, and posttraumatic stress symptoms: a prospective study of police.

Journal of psychiatric research

Inslicht SS, McCaslin SE, Metzler TJ, Henn-Haase C, Hart SL, Maguen S, Neylan TC, Marmar CR

Low expression of catecholamine-O-methyl-transferase gene in obsessive-compulsive disorder.

Journal of anxiety disorders

Wang Z, Xiao Z, Inslicht SS, Tong H, Jiang W, Wang X, Metzler T, Marmar CR, Jiang S

Trait dissociation predicts posttraumatic stress disorder symptoms in a prospective study of urban police officers.

The Journal of nervous and mental disease

McCaslin SE, Inslicht SS, Metzler TJ, Henn-Haase C, Maguen S, Neylan TC, Choucroun G, Marmar CR

A prospective study of trait anger and PTSD symptoms in police.

Journal of traumatic stress

Meffert SM, Metzler TJ, Henn-Haase C, McCaslin S, Inslicht S, Chemtob C, Neylan T, Marmar CR

Association between alexithymia and neuroendocrine response to psychological stress in police academy recruits.

Annals of the New York Academy of Sciences

McCaslin SE, Inslicht SS, Neylan TC, Metzler TJ, Otte C, Lenoci M, Henn-Haase C, Best S, Yehuda R, Marmar CR

Increased cortisol in women with intimate partner violence-related posttraumatic stress disorder.

Annals of the New York Academy of Sciences

Inslicht SS, Marmar CR, Neylan TC, Metzler TJ, Hart SL, Otte C, McCaslin SE, Larkin GL, Hyman KB, Baum A

Increased cortisol in women with intimate partner violence-related posttraumatic stress disorder.

Psychoneuroendocrinology

Inslicht SS, Marmar CR, Neylan TC, Metzler TJ, Hart SL, Otte C, McCaslin SE, Larkin GL, Hyman KB, Baum A

Posttraumatic stress associated with cancer history and BRCA1/2 genetic testing.

Psychosomatic medicine

Hamann HA, Somers TJ, Smith AW, Inslicht SS, Baum A

Similarity of prior trauma exposure as a determinant of chronic stress responding to an airline disaster.

Journal of consulting and clinical psychology

Dougall AL, Herberman HB, Delahanty DL, Inslicht SS, Baum A